Visceral leishmaniasis with haemophagocytic lymphohistiocytosis

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Hemophagocytic Lymphohistiocytosis in Children With Visceral Leishmaniasis.

Acquired hemophagocytic lymphohistiocitosis (HLH) syndrome can be a complication of visceral leishmaniasis (VL). A multicenter prospective study was conducted to determine the frequency of HLH syndrome in children with VL. Twenty-four children with VL were identified, and 10 (41%) developed HLH syndrome. VL should be ruled out in all children with HLH criteria living in or coming from endemic a...

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vISCERAL LEIShMANIASIS ASSOCIATED hEMOPhAGOCYTIC LYMPhOhISTIOCYTOSIS

www.paediatricstoday.com Visceral leishmaniasis (VL) is caused by the dissemination of the protozoan parasite Leishmania donovani throughout the reticuloendothelial system. This systemic disease may mimic or lead to several types of hematological disorders including hemophagocytic lymphohistiocytosis (HLH). Infection associated hemophagocytic syndrome caused by Leishmania is very rare and diffi...

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Review of haemophagocytic lymphohistiocytosis.

Haemophagocytic lymphohistiocytosis (HLH) describes a clinical syndrome of hyperinflammation resulting in an uncontrolled and ineffective immune response. It may develop subsequent to a number of recognised genetic mutations or in association with infection, malignancy, autoinflammatory or metabolic conditions. Even with the published diagnostic criteria it can be difficult to make the diagnosi...

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Visceral leishmaniasis and haemophagocytic syndrome in an Omani child.

The paper reports the case of a previously healthy 4-year-old-girl who presented with pallor, fever and hepatosplenomegaly. Laboratory findings included pancytopenia, hypertriglyceridemia and hyperferritinemia. Initial diagnosis of kala-azar could not be confirmed because of the absence of clinical evidence, negativity of bone marrow aspiration or specific serology for visceral leishmaniasis. R...

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Cytomegalovirus-induced haemophagocytic lymphohistiocytosis syndrome.

1 of 2 DESCRIPTION A 24-year-old female presented with fever and abdominal pain for 1 week. Her medical history included seizures secondary to tuberous sclerosis controlled with lamotrigine and Crohn’s disease in remission for the last 2 years treated with 6-mercaptopurine. On presentation, she was found to have pancytopenia and elevated liver enzymes. Physical examination was signifi cant for ...

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ژورنال

عنوان ژورنال: BMJ Case Reports

سال: 2019

ISSN: 1757-790X

DOI: 10.1136/bcr-2018-226361